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The most common dangers of LSD result from bad trips, including terrifying thoughts and feelings, despair, fear of losing control, and fear of death.

Problems that might occur include:

Extreme changes in behavior and mood; the person may sit or recline in a trance-like state
Chills, irregular breathing, sweating, trembling hands
Changes in sense of light, hearing, touch, smell, and time
Increase in blood pressure, heart rate, and blood sugar
Fatigue the next day

Are there long-term consequences to taking LSD?

Some of the long-term problems associated with chronic or heavy LSD use are: A person can experience rapidly changing feelings, immediately and long after use.
Chronic use may cause persistent problems, depression, violent behavior, anxiety, or a distorted perception of time. Large doses may cause convulsions, coma, heart/lung failure, or rupture of blood vessels in the brain.
“Flashbacks” may occur long after use.

Is there any way to reduce the risk of having a bad trip?

Here are some ways to reduce the risk of having a bad trip: Make sure you take it with someone you know and trust, preferably someone who knows how strong the effects of a hallucinogen can be.
Make sure you are somewhere where you feel safe, secure, and comfortable.
Avoid taking more.

If you’re having a bad time, avoid flashing lights and visuals and get a friend to take you to a safe, calm space.
How do I help a friend who’s having a bad trip? It is important to make your friend feel safe and comfortable, usually away from other people, visual stimulation, or noises. LSD does not produce compulsive drug-seeking behavior.